Cassava Sciences Inc

Cassava Sciences, Inc. engages in the development of novel drugs and diagnostics. It focuses on developing product candidates intended for the treatment of Alzheimer’s disease, including PTI-125 and PTI-125Dx. The company was founded by Remi Barbier and Barry M. Sherman in May 1998 and is headquartered in Austin, TX.

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Cassava Sciences advances Phase III trial with strong financial footing

Cassava Sciences is progressing well with Phase III trial milestones and financial stability, poised to announce critical trial results by year-end.
While facing challenges in data accuracy and increased expenses, the company's proactive approach and strategic planning present significant growth opportunities.
By focusing on innovation and market transformation, Cassava Sciences is positioned to redefine Alzheimer's disease diagnosis and treatment.

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Cassava Sciences, Inc. engages in the development of novel drugs and diagnostics. It focuses on developing product candidates intended for the treatment of Alzheimer’s disease, including PTI-125 and PTI-125Dx. The company was founded by Remi Barbier in May 1998 and is headquartered in Austin, TX.

AUSTIN, Texas, May 08, 2023 (GLOBE NEWSWIRE) -- Cassava Sciences, Inc. (Nasdaq: SAVA), a clinical-stage biotechnology company, today announced new data from European researchers that highlight the bioactivity of simufilam on the filamin A (FLNA) protein. Prior research has shown that FLNA is altered in pituitary tumor cells, leading to impaired cell signaling. New in vitro data now show that simufilam can reverse this FLNA alteration in pituitary tumor cells, leading to improved cell signaling. The data also suggest that improved cell signaling may enhance the clinical efficacy of an FDA-approved drug used to manage a type of pituitary tumor.

New Data by Academic Researchers Highlights Biological Activity of Simufilam on Filamin A

AUSTIN, Texas, May 01, 2023 (GLOBE NEWSWIRE) -- Cassava Sciences, Inc. (Nasdaq: SAVA), a clinical-stage biotechnology company focused on Alzheimer's disease, today announced financial results for the first quarter ended March 31, 2023. Net loss was $24.3 million, or $0.58 per share, compared to a net loss of $17.5 million, or $0.44 per share, for the same period in 2022. Net cash used in operations was $13.3 million during the first quarter of 2023. New guidance for net cash use in first half 2023 is expected to be $30 to $40 million, which is revised downward from our previous guidance of $45 to $50 million, due primarily to the timing of certain clinical payment obligations.

Cassava Sciences Reports Q1 2023 Financial Results and Operating Updates

Patient dosing for the Cognition Maintenance Study of lead candidate simufilam is slated to complete this quarter. CMS top-line results are expected in Q3.

Buy Cassava Sciences For Imminent Data Readout

AUSTIN, Texas, April 26, 2023 (GLOBE NEWSWIRE) -- Cassava Sciences, Inc. (Nasdaq: SAVA), a clinical-stage biotechnology company focused on Alzheimer's disease, today announced that Remi Barbier, President & Chief Executive Officer, has been invited to present at the 2023 H.C. Wainwright BioConnect Investor Conference in New York. In addition, management will be available for one-on-one meetings with institutional investors who are registered to attend this conference.

Cassava Sciences to Present at the 2023 H.C. Wainwright Investor Conference

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Cassava Sciences (NASDAQ: SAVA ) stock rose 11% overnight after director Richard Barry said he bought shares worth $2.3 million. The company is working on an Alzheimer's drug called Simufilam.

Insider Richard Barry Is Betting Big on Cassava (SAVA) Stock

Cassava Sciences (NASDAQ: SAVA) stock price has been in a steep sell-off in the past few months as the enthusiasm of its pipeline wanes. Shares of the biopharmaceutical company were trading at $24.9 on Wednesday, ~51% below the highest level in 2022.

Cassava Sciences stock price outlook is bearish despite insider buy

Cassava Sciences' phase 2 data was from a nonrandomized trial, therefore unconvincing. However, it indicated drug efficacy quite strongly.

Cassava Sciences: Open Label Study Data Unconvincing But Indicative Of Good Things

AUSTIN, Texas, Feb. 28, 2023 (GLOBE NEWSWIRE) -- Cassava Sciences, Inc. (Nasdaq: SAVA), a clinical-stage biotechnology company focused on Alzheimer's disease, today announced financial results for the year ended December 31, 2022, and provided operating updates. Simufilam is Cassava Sciences' oral drug candidate for the proposed treatment of Alzheimer's disease dementia.

Cassava Sciences Reports Full-year 2022 Financial Results and Operating Updates

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One in every nine seniors is living with Alzheimer's disease, and the race to cure it is worth big money. While the FDA has approved some Alzheimer's disease drugs, these can only slow the progression, not halt or reverse it.

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AUSTIN, Texas, Feb. 08, 2023 (GLOBE NEWSWIRE) -- Cassava Sciences, Inc. (Nasdaq: SAVA), a clinical-stage biotechnology company, today announced an update on patient enrollment for its on-going Phase 3 clinical studies of simufilam for the treatment of Alzheimer's disease dementia. Simufilam, an oral drug, is Cassava Sciences' proprietary lead drug candidate.

Cassava Sciences Announces Patient Enrollment Update for Phase 3 Studies of Simufilam for the Treatment of Alzheimer's Disease

It isn't about running out of money, but it's still laden with risk.

3 Big Reasons to Sell Cassava Sciences Stock Right Now

Casava Sciences Inc (NASDAQ: SAVA) stock has been the topic of much controversy in its quest for FDA approval for its simufilam drug. The Company is a clinical-stage biotechnology firm that develops drugs for Alzheimer's disease (AD).

Cassava Sciences Stock Undervalued with Its $124 Price Target?

Cassava Sciences' Simufilam staved off cognitive decline in mild Alzheimer's disease. The market reacted negatively anyway.

Cassava Sciences' Data Once Again Misunderstood

Cassava Sciences released data for over 200 patients in an open-label trial at 12 months. The mild AD subgroup performed unprecedentedly.

Cassava Sciences: Data For Mild Alzheimer's Disease Patients Provides Good Risk/Reward Profile

One of the biggest decliners in today's market is Cassava Sciences (NASDAQ: SAVA ). Shares of SAVA stock declined more than 20% at today's trough on the company's announced mid-stage results for its Alzheimer's treatment.

Why Is Cassava Sciences (SAVA) Stock Down 20% Today?

Cassava disappointed Tuesday with midstage results for its oral Alzheimer's treatment and SAVA stock plummeted by a double-digit percentage. The post Cassava Plummets As 'Highly Desirable' Alzheimer's Results Don't Cut It With Investors appeared first on Investor's Business Daily.

Cassava Plummets As 'Highly Desirable' Alzheimer's Results Don't Cut It With Investors

AUSTIN, Texas, Jan. 24, 2023 (GLOBE NEWSWIRE) -- Cassava Sciences, Inc. (Nasdaq: SAVA), a biotechnology company, today announced positive top-line Phase 2 results for simufilam, its oral drug candidate for Alzheimer's disease dementia. This was an open-label safety study with exploratory efficacy endpoints. The study enrolled over 200 patients with mild-to-moderate Alzheimer's disease (MMSE 16-26). Study participants were administered open-label simufilam tablets 100mg twice daily for 1 year or more. Endpoints were measured at baseline (study entry) and month 12.

Cassava Sciences Announces Positive Top-Line Clinical Results in Phase 2 Study Evaluating Simufilam in Alzheimer's Disease

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Is a Short Squeeze Coming in Cassava Sciences (SAVA) Stock?

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AUSTIN, Texas, Dec. 20, 2022 (GLOBE NEWSWIRE) -- Cassava Sciences, Inc. (Nasdaq: SAVA) announced today that a valued and long-time member of the Company, Nadav Friedmann, PhD, MD, has died following a brief journey with cancer, only recently discovered.

Cassava Sciences Mourns the Death of Board Member and Officer Nadav Friedmann, PhD, MD

Its oral drug candidate for Alzheimer's disease dementia has an upcoming readout. In other news, Cassava went on the legal counter-offensive against short sellers.

Cassava Sciences Drama Coming To A Head

The completion of part of an important study is pushing Cassava Sciences (NASDAQ: SAVA ) stock up today. This clinical-stage biotech company has been volatile this month but has overall performed well.

Why Is Cassava Sciences (SAVA) Stock Up 10% Today?

AUSTIN, Texas, Dec. 06, 2022 (GLOBE NEWSWIRE) -- Cassava Sciences, Inc. (Nasdaq: SAVA), a clinical-stage biotechnology company, today announced the completion of drug administration in an open-label study of simufilam for Alzheimer's disease. This study was designed to evaluate long-term drug safety and to measure cognitive changes (ADAS-cog) over 12 months in approximately 200 patients with mild-to-moderate Alzheimer's disease treated with open-label simufilam 100 mg twice daily. Simufilam is Cassava Sciences' oral drug candidate for Alzheimer's disease dementia.

Cassava Sciences Announces Completion of Dosing in Open-label Study of Simufilam for Alzheimer's Disease

News for Cassava Sciences Inc Stock (SAVA)