GlycoMimetics

GlycoMimetics, Inc. engages in the discovery and development of novel glycomimetic drugs to address unmet medical needs resulting from diseases in which carbohydrate biology plays a key role. It develops proprietary glycomimetics that inhibit disease related functions of carbohydrates. The company was founded by Rachel K. King and John L. Magnani on April 4, 2003 and is headquartered in Rockville, MD.

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GlycoMimetics reports strong Q4 performance and optimistic clinical advancements

GlycoMimetics delivered a robust performance in Q4 2022, driven by positive clinical outcomes and strategic financial decisions. The company's focus on uproleselan and promising interim utility analysis sets a solid foundation for future growth. While challenges like managing expenses and meeting trial milestones exist, GlycoMimetics is well-positioned to capitalize on opportunities in the biopharmaceutical sector.

GlycoMimetics excels in AML trials, secures funding for future growth

GlycoMimetics showcased strong performance in both clinical trials and financial standing, positioning the company well for future growth.
While challenges in managing expenses and navigating industry complexities exist, opportunities for expansion and innovation through partnerships are promising.

GlycoMimetics advances clinical trials and secures funding until late 2024

GlycoMimetics showcased strong progress in their clinical trials and financial stability during the Q2 2023 Earnings Call. With FDA clearance for Phase III uproleselan study and a cash runway until late 2024, the company is well-positioned for future growth. Challenges include successful trial execution and maintaining financial discipline.

GlycoMimetics progresses in AML trials, eyes positive Phase III results

GlycoMimetics demonstrated strong performance in advancing its clinical pipeline, with a focus on uproleselan in AML.
While facing challenges like delays in studies and increased expenses, the company remains optimistic about future prospects.
Opportunities lie in presenting data at conferences, exploring market expansion, and anticipating positive Phase III results by Q2 2024.

GlycoMimetics reports progress in trials and financial strength for growth

GlycoMimetics' Q4 2023 earnings call showcased positive clinical trial outcomes, strong financial standing, and a strategic focus on addressing unmet medical needs. The company's upcoming milestones, including the Phase III trial results and NDA submission, indicate promising growth potential.

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ROCKVILLE, Md.--(BUSINESS WIRE)--GlycoMimetics, Inc. (Nasdaq: GLYC) today announced that Chief Executive Officer Harout Semerjian will present at the upcoming H.C. Wainwright & Co 23rd Annual Global Investment Virtual Conference taking place September 13-15, 2021. The presentation will be available on the company's website at the “Investors” tab for 30 days, beginning Monday, September 13 at 7:00 a.m. EDT. To access the live webcast and subsequent archived recordings for the presentation, p

GlycoMimetics to Present at Upcoming H.C. Wainwright & Co Annual Global Investment Virtual Conference

Investors need to pay close attention to GlycoMimetics (GLYC) stock based on the movements in the options market lately.

Implied Volatility Surging for GlycoMimetics (GLYC) Stock Options

GlycoMimetics, Inc. (GLYC) CEO Rachel King on Q2 2021 Results - Earnings Call Transcript

ROCKVILLE, Md.--(BUSINESS WIRE)--GlycoMimetics, Inc. (Nasdaq: GLYC) today reported its financial results for the quarter ended June 30, 2021 and highlighted recent events. Cash and cash equivalents at June 30, 2021 were $118.9 million. “There are now six trials underway evaluating our lead clinical candidate, uproleselan, including three registration trials and three ISTs, which we anticipate will provide clinical data flow beginning in 2022. Importantly, recruitment rates in both our Company-s

GlycoMimetics Reports Highlights and Financial Results for Second Quarter 2021

ROCKVILLE, Md.--(BUSINESS WIRE)--GlycoMimetics, Inc. (Nasdaq: GLYC) today announced that its Board of Directors has appointed Harout Semerjian as chief executive officer (CEO), effective August 6, 2021, to succeed retiring Founding CEO Rachel King. Mr. Semerjian, a seasoned executive with strong oncology commercialization experience, will lead the company as it advances its registrational trials on its lead clinical candidate, uproleselan, in acute myeloid leukemia (AML), accelerates planning f

GlycoMimetics Names Harout Semerjian as New Chief Executive Officer to Succeed Retiring CEO Rachel King

ROCKVILLE, Md.--(BUSINESS WIRE)--GlycoMimetics, Inc. (Nasdaq: GLYC) announced today that it will host a conference call and webcast to report its second quarter financial results on Thursday, August 5, 2021, at 8:30 a.m. ET. The dial-in number for the conference call is (844) 413-7154 for domestic participants and (216) 562-0466 for international participants, with participant code 9977599. Participants are encouraged to connect 15 minutes in advance of the call to ensure they are able to conne

GlycoMimetics to Report Second Quarter Financial Results on August 5, 2021

ROCKVILLE, Md.--(BUSINESS WIRE)--GlycoMimetics, Inc. (Nasdaq: GLYC) announced today that clinicians have treated the first patient in a Phase 1b/2 study evaluating the company's lead drug candidate, uproleselan, added to cladribine plus low dose cytarabine (LDAC) in patients with treated secondary AML (ts-AML). The investigator-sponsored trial is being led by Tapan Kadia, M.D., associate professor of Leukemia at The University of Texas MD Anderson Cancer Center. According to Eric Feldman, M.D.,

Trial Launches to Evaluate GlycoMimetics' Uproleselan Added to Cladribine Plus Low-Dose Cytarabine in AML Patients

ROCKVILLE, Md.--(BUSINESS WIRE)--GlycoMimetics, Inc. (Nasdaq: GLYC) announced today that clinicians at University of California (UC) Davis Comprehensive Cancer Center initiated dosing of the first patient in a clinical study of uproleselan combined with venetoclax and azacitidine for the treatment of older or unfit patients with treatment-naïve acute myeloid leukemia (AML). Brian A. Jonas, MD, PhD, FACP, UC Davis Division of Hematology/Oncology, is the clinical trial's principal investigator. A

GlycoMimetics Announces Initiation of Clinical Trial Evaluating Uproleselan in Combination With Venetoclax and Azacitidine

ROCKVILLE, Md.--(BUSINESS WIRE)--GlycoMimetics, Inc. (Nasdaq: GLYC), today announces that Chief Executive Officer Rachel King will provide a company overview at the Jefferies 2021 Virtual Healthcare Conference. Ms. King's presentation will take place from 2:30 to 2:55 p.m. on June 3, 2021. More information is available in the Investors section of the GlycoMimetics website. About GlycoMimetics, Inc. GlycoMimetics is a clinical-stage biotechnology company discovering and developing glycobiology-b

GlycoMimetics to Present at Jefferies 2021 Virtual Healthcare Conference

ROCKVILLE, Md.--(BUSINESS WIRE)--GlycoMimetics, Inc. (Nasdaq: GLYC) announced today that clinicians at Washington University School of Medicine in St. Louis have dosed the first patient in an investigator-sponsored trial (IST) evaluating uproleselan as a prophylactic agent to reduce gastrointestinal (GI) toxicities associated with high-dose melphalan in autologous hematopoietic cell transplantation (auto-HCT) for multiple myeloma (MM). Dr. Keith Stockerl-Goldstein, M.D., Professor of Medicine,

GlycoMimetics Announces Investigator-Sponsored Phase 2 Clinical Trial Evaluating Uproleselan for Prevention of Gastro-Intestinal Toxicity in Autologous Hematopoietic Cell Transplantation

GlycoMimetics is priced based on a prior Phase 3 clinical trial failure. But it had strong Phase 2 acute myeloid leukemia data.

GlycoMimetics A Buy On Potential 2022 AML Data

GlycoMimetics, Inc. (GLYC) CEO Rachel King on Q1 2021 Results - Earnings Call Transcript

ROCKVILLE, Md.--(BUSINESS WIRE)--GlycoMimetics, Inc. (Nasdaq: GLYC) today reported its financial results for the quarter ended March 31, 2021 and highlighted recent company events. Cash and cash equivalents at March 31, 2021 were $132.5 million. “Our recent achievements, both in our collaboration with Apollomics and in data presentations at AACR, underscore the productivity of our pipeline. Working closely with investigators, regulators and collaborators, we are seeing great enthusiasm for our

GlycoMimetics Reports Highlights and Financial Results for First Quarter 2021

ROCKVILLE, Md.--(BUSINESS WIRE)--GlycoMimetics, Inc. (Nasdaq: GLYC), today announces that it will host a conference call and webcast to report first quarter financial results on Monday, May 3, 2021, at 8:30 a.m. ET. The dial-in number for the conference call is (844) 413-7154 for domestic participants or (216) 562-0466 for international participants, with participant code 9891637. Participants are encouraged to connect 15 minutes in advance of the call to ensure that all callers are able to con

GlycoMimetics to Report First Quarter Financial Results on May 3, 2021

ROCKVILLE, Md.--(BUSINESS WIRE)--GlycoMimetics, Inc. (Nasdaq: GLYC) today announces that an abstract presenting the results of a recent preclinical study on the therapeutic effects of GMI-1757, a new glycomimetic with dual antagonism to E-selectin and galectin-3, has been accepted for a poster presentation at the American Association of Cancer Research (AACR) 2021 Annual Meeting, to be held virtually on April 10-15 and May 17-21. The study demonstrates that GMI-1757 significantly improved anti-

GlycoMimetics to Present at AACR 2021 Meeting on Positive Therapeutic Effects of GMI-1757 in a Pancreatic Adenocarcinoma Model

ROCKVILLE, Md.--(BUSINESS WIRE)--GlycoMimetics, Inc. (Nasdaq: GLYC) today announces that a Phase 1b trial of GMI-1359, being conducted at Duke University Cancer Center, showed evidence of on-target effects, immune-activation and cell mobilization in the initial two patients treated with the Company's dual antagonist of E-selectin and CXCR4. Dorothy Sipkins, MD, PhD, Associate Research Professor in Pharmacology and Cancer Biology at Duke University School of Medicine, will present results from t

Positive Findings From Phase 1b Trial of GlycoMimetics' GMI-1359 To Be Presented at AACR 2021 Meeting

ROCKVILLE, Md.--(BUSINESS WIRE)--GlycoMimetics, Inc. (Nasdaq: GLYC) today announces that an abstract presenting the interim analysis of a Phase 1b proof-of-concept study of GMI-1359, the Company's dual antagonist of E-selectin and CXCR4, has been accepted for presentation at the American Association of Cancer Research (AACR) 2021 Annual Meeting, to be held virtually on April 10-15 and May 17-21. Preclinical studies indicate that targeting both E-selectin and CXCR4, a chemokine receptor, with a

GlycoMimetics to Share GMI-1359 and Galectin-3 Antagonist Program Data at AACR 2021 Meeting

ROCKVILLE, Md.--(BUSINESS WIRE)--GlycoMimetics (Nasdaq: GLYC) today announced that Apollomics has dosed the first patient in China in a Phase 1 clinical trial of APL-106 (uproleselan injection) for the treatment of adults with relapsed or refractory acute myeloid leukemia (AML). In February of this year, Apollomics initiated two Phase 1 study sites in Greater China. “Dosing of the first patient in Greater China is a significant accomplishment for Apollomics. Equally important is the fact that A

Apollomics, Inc Doses First Patient in Phase 1 Clinical Trial in China of GlycoMimetics' Uproleselan for the Treatment of AML

GlycoMimetics, Inc.'s (GLYC) CEO Rachel King on Q4 2020 Results - Earnings Call Transcript

ROCKVILLE, Md.--(BUSINESS WIRE)--GlycoMimetics, Inc. (Nasdaq: GLYC) today reported its financial results for the fourth quarter and year ended December 31, 2020, and highlighted recent Company events, including several accomplishments reported to date in 2021. Cash and cash equivalents at December 31, 2020 were $137.0 million. “During 2020, we remained on track to complete enrollment of our uproleselan pivotal trial in the second half of 2021. Uproleselan continues to have strong support from c

GlycoMimetics Reports Highlights and Financial Results for Fourth Quarter and Full Year 2020

ROCKVILLE, Md.--(BUSINESS WIRE)--GlycoMimetics, Inc. (Nasdaq: GLYC), today announces that executives from the Company plan to participate in three virtual healthcare conferences in March. More information about the presentations and panel discussions will be available on the Company's website, under the Investors tab. Details are as follows: Cowen 41st Annual Health Care Conference March 1 – March 4, 2021 Eric Feldman, M.D., GlycoMimetics Vice President, Clinical Development, to participate in

GlycoMimetics to Present at Three Upcoming Virtual Healthcare Investor Conferences

ROCKVILLE, Md.--(BUSINESS WIRE)--GlycoMimetics, Inc. (Nasdaq: GLYC), today announces that it will host a conference call and webcast to report fourth quarter and year-end 2020 financial results on Tuesday, March 2, 2021, at 8:30 a.m. ET. The dial-in number for the conference call is (844) 413-7154 for domestic participants or (216) 562-0466 for international participants, with participant code 1034166. Participants are encouraged to connect 15 minutes in advance of the call to ensure that all c

GlycoMimetics to Report Fourth Quarter and Year-End 2020 Financial Results on March 2

ROCKVILLE, Md.--(BUSINESS WIRE)--GlycoMimetics, Inc. (Nasdaq: GLYC) today announced the promotion of Eric Feldman, M.D., to Senior Vice President and Chief Medical Officer. Dr. Feldman joined the Company in 2019 and was previously Vice President, Global Clinical Development. “Eric is internationally recognized for his work in the development of new therapies for the treatment of leukemias and related bone marrow disorders, and in the past two years, has established himself as a leader in our ma

GlycoMimetics Promotes Dr. Eric Feldman to Chief Medical Officer

ROCKVILLE, Md.--(BUSINESS WIRE)--GlycoMimetics (Nasdaq: GLYC) today in an oral presentation at the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition disclosed new data reinforcing a now comprehensive set of findings that underscore the improvement of rivipansel when administered early during an acute vaso-occlusive crisis (VOC) in individuals with sickle cell disease (SCD). The new data were part of an analysis of an Open Label Extension (OLE) trial of rivipansel, designed

New Supportive Efficacy Data for GlycoMimetics' Rivipansel in Sickle Cell Acute Vaso-Occlusive Crisis Presented at 62nd ASH Annual Meeting and Exposition

ROCKVILLE, Md.--(BUSINESS WIRE)--GlycoMimetics' (Nasdaq: GLYC) product candidate uproleselan — when added to a combination therapy of venetoclax and a hypomethylating agent (HMA) — was shown today in an oral presentation to break chemoresistance by dramatically and significantly reducing tumor burden as detected by circulating human AML cells after three weeks of treatment, and by significantly increasing survival (p = 0.0009) in an animal model engrafted with AML from a patient with acquired r

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